Dr. Jonathan Ransom, world-class mountaineer and surgeon, is climbing in the Swiss Alps with his beautiful wife, Emma, when a blizzard sets in. In their bid to escape the storm, Emma is killed when she falls into a hidden crevasse. Twenty-four hours later, Jonathan receives an envelope addressed to his wife containing two baggage-claim tickets. Puzzled, he journeys to a remote railway station only to find himself in a life-and-death struggle for his wife's possessions. Suddenly the subject of an international manhunt and the target of a master assassin, Jonathan is forced on the run. His only chance at survival lies in uncovering the devastating truth behind the secret his wife kept from him and in stopping the terrifying conspiracy that threatens to bring the world to the brink of annihilation.