Sookie Stackhouse is a cocktail waitress in small-town Louisiana, but she keeps to herself and doesn't date much because of her "disability" to read minds. When she meets Bill, Sookie can't hear a word he's thinking. He's the type of guy she's waited for all of her life, but he has a disability, too--he's a vampire with a bad reputation. When one of Sookie's coworkers is killed, she fears she's next.